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Provedor de dados:  BABT
País:  Brazil
Título:  Determination of N-nitrosamines and N-nitrosables substances in rubber teats and sothers by GC-TEA
Autores:  Vieira,Eleno Rodrigues
Pierozan,Nilso José
Lovison,Viviane
Data:  2006-01-01
Ano:  2006
Palavras-chave:  N-Nitrosamines
Method
Nipples and pacifiers
Resumo:  N-Nitrosamines are receiving special attention because they present high mutagenic and carcinogenic potential. They can be found in several areas. In rubber, for example, they can be found in Nipples and Pacifiers. Spiegelhalder and Pressumann, have observed that N-Nitrosamines present in nipples and pacifiers could easily migrate to artificial saliva. They have also observed that a considerable amount of N-Nitrosamines precursors, such as nitrosable amines, could migrate to saliva, increasing the possibility of N-Nitrosamines formation into the stomach of living beings. In 80's, Holland, Germany and FDA-U.S.A. have established volatile N-Nitrosamines limit levels. In 2002, in Brazil, limit levels came through Resolução RDC n° 221 of ANVISA. This resolution refers to NBR10334 and NBR 13793 standards where limits and analysis methods are specified. In this work SENAICETEPO presents the method adopted for determination of N-Nitrosamines and N-Nitrosables in nipples and pacifiers. The detection and determination limits of the analytical system as well the method uncertainty were evaluated, in order to demonstrate the adequacy of this technique to comply with the requirements of NBR10334/2003 and NBR 13793/2003 standard.
Tipo:  Info:eu-repo/semantics/article
Idioma:  Inglês
Identificador:  http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132006000200012
Editor:  Instituto de Tecnologia do Paraná - Tecpar
Relação:  10.1590/S1516-89132006000200012
Formato:  text/html
Fonte:  Brazilian Archives of Biology and Technology v.49 n.spe 2006
Direitos:  info:eu-repo/semantics/openAccess
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